Bilateral chest wall sarcomas associated with silicone implant capsules in a patient with Li-Fraumeni syndrome
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چکیده
Introduction: the carcinogenicity of silicone implants has been confirmed in rodents but is not evident in human breast. case report: We report a patient with Li-Fraumeni syndrome who developed bilateral chest wall unclassified sarcomas tightly associated with the capsule of silicone implants placed during treatment for her right breast cancer. conclusion: Our case may suggest that genetic instability could increase the probability of carcinogenesis of silicone implants. caution should be exercised when making management plans for these patients.
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تاریخ انتشار 2016